The PCI-P16C16U Universal PCI card supports the 3.3 V/5 V PCI bus and provides 16 optically-isolated Digital Input channels and 16 open-collector (Sink, NPN) Digital Output channels. The DI channels provide 5000 Vrms isolation protection that allows the input signals to be completely floated so as to prevent ground loops and isolate the host computer from potentially damaging voltage spikes. The open-collector DO channels are typically used for alarm and warning notifications, control of signal output, control of external circuits that require a higher voltage level, or signal transmission applications, etc. The PCI-P16C16U contains a single DB-37 connector and a single 40-pin box header, and includes a 40-pin to DB-37 flat cable for easy wiring.

The PCI-P16C16U cards also includes an onboard Card ID switch that enables the board to be recognized via software if two or more boards are installed in the same computer.